Kato H, Ogihara S, Kobayashi Y, Toguri A G, Igawa Y, Nishizawa O
Department of Urology, Komoro Kosei Hospital, Japan.
Int J Urol. 1998 May;5(3):291-3. doi: 10.1111/j.1442-2042.1998.tb00606.x.
Paraurethral glands of the female urethra, which are assumed to be embryologically homologous to the male prostate gland, are possible origins for diverticular cancer of the urethra. A case of primary adenocarcinoma arising in a female urethral diverticulum is presented. Pathology revealed a columnar/mucinous type adenocarcinoma which stained positively for carcinoembryonic antigen (CEA) and negatively for PSA. Normal paraurethral ducts located near the urethra and normal urethral epithelium also stained positively for CEA. These findings suggest that the adenocarcinoma in our case originated from the paraurethral duct near the urethral lumen.
女性尿道旁腺在胚胎学上被认为与男性前列腺同源，可能是尿道憩室癌的起源部位。本文报告一例发生于女性尿道憩室的原发性腺癌。病理检查显示为柱状/黏液型腺癌，癌胚抗原（CEA）染色阳性，前列腺特异性抗原（PSA）染色阴性。位于尿道附近的正常尿道旁腺导管及正常尿道上皮CEA染色也呈阳性。这些结果提示，本例腺癌起源于尿道腔内附近的尿道旁腺导管。
