Bogetto F, Maina G, Ferro G, Carbone M, Gandolfo S
Department of Neuroscience, University of Turin, Italy.
Psychosom Med. 1998 May-Jun;60(3):378-85. doi: 10.1097/00006842-199805000-00028.
The goal of this study was to evaluate the prevalence and type of psychiatric disorders coexisting with burning mouth syndrome (BMS), to compare the clinical features of patients with BMS alone with patients with multiple diagnoses, and to investigate the number and severity of life events that occur before the onset of BMS.
There were 102 patients with BMS, with no possible local or systemic causes, who were evaluated according to the diagnostic criteria of DSM-IV. All axis I diagnoses for which the patients met criteria at intake or lifetime were determined. Life events were evaluated for a period of 6 months before the onset of BMS. A statistical comparison between patients and a matched control group was performed first; moreover, patients with BMS alone were compared with patients with comorbid BMS.
Although 29 (28.4%) BMS patients were not given any other lifetime psychiatric diagnosis, high rates of comorbid psychiatric diagnoses were found. The most prevalent concurrent diagnoses were depressive disorders and generalized anxiety disorder. No significant differences emerged in clinical features between patients with and without other current psychiatric disorders. The severity of life events, rather than in their number, was significantly associated with BMS.
BMS has high psychiatric comorbidity but can occur in the absence of psychiatric diagnoses.
本研究旨在评估与灼口综合征(BMS)共存的精神障碍的患病率和类型,比较单纯BMS患者与多重诊断患者的临床特征,并调查BMS发病前发生的生活事件的数量和严重程度。
对102例无可能的局部或全身病因的BMS患者,根据《精神疾病诊断与统计手册》第四版(DSM-IV)的诊断标准进行评估。确定患者在初诊或终生符合标准的所有轴I诊断。对BMS发病前6个月的生活事件进行评估。首先对患者与匹配的对照组进行统计学比较;此外,将单纯BMS患者与合并BMS的患者进行比较。
虽然29例(28.4%)BMS患者未被给予任何其他终生精神疾病诊断,但发现合并精神疾病诊断的比例很高。最常见的并发诊断是抑郁症和广泛性焦虑症。有或无其他当前精神疾病的患者在临床特征上没有显著差异。生活事件的严重程度而非数量与BMS显著相关。
BMS有较高的精神疾病共病率,但可在无精神疾病诊断的情况下发生。