Schenck N L, Tomlinson M J, Ridgley C D
Arch Otolaryngol. 1976 Sep;102(9):524-8. doi: 10.1001/archotol.1976.00780140056003.
Frontal osteoplasty with exogenous material has been uniformly unsuccessful both experimentally and clinically. Our experiment was designed to test the long-term behavior of a new poly (tetrafluoroethylene)-carbon fiber implant material (Proplast) in a canine frontal sinus model. Varying conditions such as removal of the sinus mucoperiosteum, closure of the nasofrontal ducts, exposure of dura mater, and cerebrospinal fluid leaks were studied at intervals up to one year. Proplast was 100% successful in obliteration of the canine frontal sinus. The ultraporous nature allowed rapid vascularization, collagen ingrowth, and new bone formation, and led to stabilization rather than sequestration. Frontal obliteration with Proplast may be clinically superior to osteoplasty with any other presently available exogenous material or with osteoneogenesis alone, and may even obviate the few complications encountered with adipose implants. Only longer range experimental and clinical evaluation will provide the answer.
使用外源材料进行额骨成形术在实验和临床中均一直未取得成功。我们的实验旨在测试一种新型聚四氟乙烯 - 碳纤维植入材料（普罗普拉斯）在犬额窦模型中的长期性能。我们对诸如去除窦黏膜骨膜、封闭鼻额管、暴露硬脑膜和脑脊液漏等不同情况进行了长达一年的间隔研究。普罗普拉斯在闭塞犬额窦方面100%成功。其超多孔性质允许快速血管化、胶原长入和新骨形成，并导致稳定而非骨分离。使用普罗普拉斯进行额部闭塞在临床上可能优于使用任何其他现有外源材料或单独进行骨生成的额骨成形术，甚至可能避免脂肪植入物所遇到的少数并发症。只有更长时间的实验和临床评估才能给出答案。
