Horowitz Gilad, Amit Moran, Ben-Ari Oded, Gil Ziv, Abergel Abraham, Margalit Nevo, Cavel Oren, Wasserzug Oshri, Fliss Dan M
Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Department of Otolaryngology and Head & Neck Surgery, Rambam Medical Center, Haifa, Israel.
PLoS One. 2013 Dec 23;8(12):e83820. doi: 10.1371/journal.pone.0083820. eCollection 2013.
To compare frontal sinus cranialization to obliteration for future prevention of secondary mucocele formation following open surgery for benign lesions of the frontal sinus.
Retrospective case series.
Tertiary academic medical center.
Sixty-nine patients operated for benign frontal sinus pathology between 1994 and 2011.
Open excision of benign frontal sinus pathology followed by either frontal obliteration (n = 41, 59%) or frontal cranialization (n = 28, 41%).
The prevalence of post-surgical complications and secondary mucocele formation were compiled.
Pathologies included osteoma (n = 34, 49%), mucocele (n = 27, 39%), fibrous dysplasia (n = 6, 9%), and encephalocele (n = 2, 3%). Complications included skin infections (n = 6), postoperative cutaneous fistula (n = 1), telecanthus (n = 4), diplopia (n = 3), nasal deformity (n = 2) and epiphora (n = 1). None of the patients suffered from postoperative CSF leak, meningitis or pneumocephalus. Six patients, all of whom had previously undergone frontal sinus obliteration, required revision surgery due to secondary mucocele formation. Statistical analysis using non-inferiority test reveal that cranialization of the frontal sinus is non-inferior to obliteration for preventing secondary mucocele formation (P<0.0001).
Cranialization of the frontal sinus appears to be a good option for prevention of secondary mucocele development after open excision of benign frontal sinus lesions.
比较额窦颅骨化术与额窦闭塞术在预防额窦良性病变开放手术后继发黏液囊肿形成方面的效果。
回顾性病例系列研究。
三级学术医疗中心。
1994年至2011年间因额窦良性病变接受手术的69例患者。
开放性切除额窦良性病变,随后进行额窦闭塞术(n = 41,59%)或额窦颅骨化术(n = 28,41%)。
汇总术后并发症和继发黏液囊肿形成的发生率。
病变包括骨瘤(n = 34,49%)、黏液囊肿(n = 27,39%)、纤维发育不良(n = 6,9%)和脑膨出(n = 2,3%)。并发症包括皮肤感染(n = 6)、术后皮肤瘘(n = 1)、内眦距增宽(n = 4)、复视(n = 3)、鼻畸形(n = 2)和溢泪(n = 1)。所有患者均未出现术后脑脊液漏、脑膜炎或气颅。6例患者因继发黏液囊肿形成需要再次手术,这些患者均曾接受额窦闭塞术。使用非劣效性检验的统计分析表明,在预防继发黏液囊肿形成方面,额窦颅骨化术不劣于额窦闭塞术(P<0.0001)。
对于预防额窦良性病变开放切除术后继发黏液囊肿的发生,额窦颅骨化术似乎是一个不错的选择。