非快速眼动睡眠中频繁短暂觉醒对非快速眼动-快速眼动睡眠周期的影响。

Effect of frequent brief awakenings from nonREM sleep on the nonREM-REM sleep cycle.

作者信息

Endo T, Roth C, Landolt H P, Werth E, Aeschbach D, Achermann P, Borbély A A

机构信息

Institute of Pharmacology, University of Zürich, Switzerland.

出版信息

Psychiatry Clin Neurosci. 1998 Apr;52(2):129-30. doi: 10.1111/j.1440-1819.1998.tb00988.x.

DOI:10.1111/j.1440-1819.1998.tb00988.x

PMID:9628109

Abstract

In the framework of a selective sleep deprivation study, eight young men were repeatedly awakened during 3 nights from nonREM sleep (nonREMS). The mean number of awakenings per night was 27.4, 29.5 and 32.8. In order to avoid excessive suppression of slow wave sleep, no awakening occurred in the first nonREMS episode. Compared to baseline, cycle 2 was significantly prolonged in all 3 nights, and cycle 3 in night 3 only. However, after subtracting the waking intervals, the differences from baseline was eliminated. The results show that the mechanisms underlying sleep cycle control keep track of sleep time and disregard epochs of waking.

摘要

在一项选择性睡眠剥夺研究的框架内，八名年轻男性在三个晚上的非快速眼动睡眠（nonREMS）期间被反复唤醒。每晚的平均唤醒次数分别为27.4、29.5和32.8。为避免过度抑制慢波睡眠，在首个非快速眼动睡眠阶段未进行唤醒。与基线相比，在所有三个晚上，第2个睡眠周期均显著延长，仅在第3晚第3个睡眠周期延长。然而，在减去清醒间隔后，与基线的差异消除。结果表明，睡眠周期控制的潜在机制记录睡眠时间并忽略清醒时段。