Shiotsuka S, Atsumi Y, Ogata S, Yamamoto R, Igawa M, Takahashi K, Hirasawa H, Koyama K, Maki A, Yamashita Y, Koizumi H, Toru M
Saitama Comprehensive Mental Health Center, Japan.
Psychiatry Clin Neurosci. 1998 Apr;52(2):172-3. doi: 10.1111/j.1440-1819.1998.tb01012.x.
We investigated the relationship between hemodynamic changes in the cortex measured by near-infrared spectroscopy (NIRS) and the polysomnographic changes during sleep. Four healthy male volunteers participated in the study. Near-infrared spectroscopy measuring and polysomnographic recordings were done simultaneously during sleep. In many case, oxy-hemoglobin (oxy-Hb) decreased and deoxy-hemoglobin (deoxy-Hb) increased during the transition from wakefulness to sleep, and oxy-Hb increased toward deep sleep. Oxy-Hb and deoxy-Hb had larger fluctuations during REM sleep than those during non-REM sleep. During REM sleep, oxy-Hb often showed a lower level and deoxy-Hb showed a higher level than those during the preceding and following non-REM sleep.
我们研究了通过近红外光谱（NIRS）测量的皮质血流动力学变化与睡眠期间多导睡眠图变化之间的关系。四名健康男性志愿者参与了该研究。在睡眠期间同时进行近红外光谱测量和多导睡眠图记录。在许多情况下，从清醒到睡眠的过渡过程中，氧合血红蛋白（oxy-Hb）减少，脱氧血红蛋白（deoxy-Hb）增加，并且氧合血红蛋白在深度睡眠时增加。快速眼动睡眠期间氧合血红蛋白和脱氧血红蛋白的波动比非快速眼动睡眠期间更大。在快速眼动睡眠期间，氧合血红蛋白通常显示出比之前和之后的非快速眼动睡眠更低的水平，而脱氧血红蛋白则显示出更高的水平。
