Tanabe E, Yara K, Mastuura M, Takahashi S, Sakai T, Kojima T
Department of Neuropsychiatry, Nihon University School of Medicine, Tokyo, Japan.
Psychiatry Clin Neurosci. 1998 Apr;52(2):204-5. doi: 10.1111/j.1440-1819.1998.tb01032.x.
An 18-year-old male patient with recurrent hypersomnia (RH) was evaluated using prolonged polysomnography (PSG). During symptomatic period (SMP), the patient showed both 'dissociated stage REM' (DREM), REM sleep without muscle atonia and 'dissociated stage 1' (DSt-1), and stage 1 sleep with rapid eye movement. These stages were observed in the morning or following daytime record. They decreased during asymptomatic period (ASMP). It has been said that RH is caused by dysfunction of the hypothalamus and midbrain limbic system. The present result suggests also that RH involves dysfunction of the brain stem.
一名患有复发性嗜睡症(RH)的18岁男性患者接受了长时间多导睡眠图(PSG)评估。在症状期(SMP),患者出现了“分离性快速眼动睡眠期”(DREM,即无肌肉弛缓的快速眼动睡眠)和“分离性1期”(DSt-1,即伴有快速眼动的1期睡眠)。这些阶段在早晨或白天记录后被观察到。在无症状期(ASMP)它们减少。据说RH是由下丘脑和中脑边缘系统功能障碍引起的。目前的结果还表明RH涉及脑干功能障碍。