Watanabe T, Kato M, Sekimoto M, Kajimura N, Takahashi K
National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.
Psychiatry Clin Neurosci. 1998 Apr;52(2):255-6. doi: 10.1111/j.1440-1819.1998.tb01061.x.
We examined polysomnography (PSG) and body temperature in a patient with delayed sleep phase syndrome who responded to phototherapy. The patient was a 31-year-old woman whose condition had slightly improved by a vitamin B12 administration. Phototherapy was administered to her in combination with the vitamin B12 medication, and this combined treatment successfully advanced her delayed sleep phase. On PSG, the regimen showed shortened sleep latency, decreased total sleep time and stages 1 and 2 sleep, and increased slow wave sleep. Phototherapy also improved temporal distribution of delta half-waves (0.5-2.0 Hz, > or = 31 microV) as well as phase relationship between sleep and body temperature.
我们对一名患有睡眠时相延迟综合征且对光疗有反应的患者进行了多导睡眠图(PSG)和体温检查。该患者为一名31岁女性,其病情通过维生素B12给药稍有改善。对她联合使用维生素B12药物进行光疗,这种联合治疗成功地提前了她延迟的睡眠时相。在多导睡眠图上,该治疗方案显示睡眠潜伏期缩短、总睡眠时间以及1期和2期睡眠时间减少,慢波睡眠增加。光疗还改善了δ半波(0.5 - 2.0赫兹,≥31微伏)的时间分布以及睡眠与体温之间的相位关系。