Shibui K, Okawa M, Uchiyama M, Ozaki S, Kamei Y, Hayakawa T, Urata J
Department of Psychophysiology, National Institute of Mental Health, National Center of Neurology and Psychiatry, Chiba, Japan.
Psychiatry Clin Neurosci. 1998 Apr;52(2):236-7. doi: 10.1111/j.1440-1819.1998.tb01050.x.
The onset of the low temperature (LT) zone which was defined as a period when the rectal temperature was below its daily mean is a convenient circadian phase marker. In this study, we document three cases of non-24 h sleep-wake syndrome in which identification of the LT zone as an evening circadian phase marker contributed to clinical judgments. We found that the LT zone was correlated well with dim light melatonin onset. Moreover, calculating the LT zone was useful in determining phase position in irregular sleep pattern and in determining the timing of bright light therapy.
将直肠温度低于其每日均值的时间段定义为低温（LT）区，它是一个方便的昼夜节律相位标记。在本研究中，我们记录了3例非24小时睡眠-清醒综合征病例，其中将LT区识别为傍晚的昼夜节律相位标记有助于临床判断。我们发现LT区与暗光褪黑素开始分泌的时间密切相关。此外，计算LT区有助于确定不规则睡眠模式中的相位位置以及确定强光治疗的时机。
