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婴儿脑积水:早产儿患病率下降

Infantile hydrocephalus: declining prevalence in preterm infants.

作者信息

Fernell E, Hagberg G

机构信息

Department of Pediatrics, Huddinge Hospital, Sweden.

出版信息

Acta Paediatr. 1998 Apr;87(4):392-6. doi: 10.1080/08035259850156968.

DOI:10.1080/08035259850156968
PMID:9628293
Abstract

The prevalence and aetiological panorama of infantile hydrocephalus in western Sweden have been followed since the late 1960s. A significant increase in the live birth prevalence of very preterm infants with infantile hydrocephalus was found, from 6.99 per 1000 in the birth year period 1973-78 to 25.37 in 1983-86, and owing to an increased survival of very preterm infants with a high risk of hydrocephalus, secondary to an intraventricular haemorrhage occurring in the perinatal period. In the present study covering the birth years 1991-94, a declining prevalence to 13.69 per 1000 very preterm infants was found. In moderately preterm and term groups, mostly with prenatal aetiologies, the prevalence was unchanged. Outcome in surviving children with infantile hydrocephalus remained essentially the same as in previous studies, indicating that the underlying aetiology is the most decisive factor with respect to ensuing neuroimpairments.

摘要

自20世纪60年代末以来,瑞典西部一直追踪婴儿脑积水的患病率和病因全貌。发现患有婴儿脑积水的极早产儿的活产患病率显著增加,从1973 - 1978年出生年份期间的每1000例中有6.99例增加到1983 - 1986年的25.37例,这是由于患有脑积水高风险的极早产儿存活率增加,这继发于围生期发生的脑室内出血。在本研究涵盖的1991 - 1994年出生年份中,发现患病率下降至每1000例极早产儿中有13.69例。在中度早产和足月儿组中,大多为产前病因,患病率没有变化。存活的婴儿脑积水患儿的结局与先前研究基本相同,表明潜在病因是随后神经损伤的最决定性因素。

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