Krishnan K, Ruffin M T, Brenner D E
Department of Internal Medicine, East Tennessee State University, Johnson City, Tennessee, USA.
Prim Care. 1998 Jun;25(2):361-79. doi: 10.1016/s0095-4543(05)70069-5.
Cancer chemoprevention uses noncytotoxic drugs or nutrients to prevent, retard, or delay carcinogenesis. The future of cancer chemoprevention depends on understanding key cellular growth and proliferation-controlling events, developing markers of molecular carcinogenesis, surrogate endpoint biomarkers, and targeted chemopreventive approaches.
癌症化学预防采用非细胞毒性药物或营养物质来预防、延缓或推迟癌症发生。癌症化学预防的未来取决于对关键细胞生长和增殖控制事件的理解、开发分子致癌作用的标志物、替代终点生物标志物以及靶向化学预防方法。
