Ortega López D, Martínez Sarmiento J, Borque M, Fernández D, Sobrino J A, Hernández C, Alvarez M, Alvarez Fernández-Represa J
Servicio de Cirugía General I, Hospital Universitario San Carlos, Madrid.
An Med Interna. 1998 May;15(5):250-4.
A study in humans of the profile of physiologic secretion, basal and postprandial of three gastrointestinal peptides has been carried out.
20 healthy subjects were studied (9 women and 11 men); any previous digestive pathology has not been included. The study was carried out by determining P substance, neurotensin and somatostatin in plasma by means of RIA I125. The subjects were studied in basal conditions of fasting and the samples were taken at 30, 60 and 90 minutes intervals after the oral intake of a semi-liquid preparation made up of the three immediate principles.
It shows the secretion curve of the three gastrointestinal peptides, in a global way and also in relation to sex, age and body weight.
对三种胃肠肽的生理分泌情况进行了一项人体研究，包括基础分泌和餐后分泌。
研究了20名健康受试者（9名女性和11名男性）；未纳入任何既往消化疾病史。通过I125放射免疫分析法测定血浆中的P物质、神经降压素和生长抑素进行该研究。在空腹的基础状态下对受试者进行研究，并在口服由三种主要成分制成的半流质制剂后，每隔30、60和90分钟采集样本。
以整体方式以及与性别、年龄和体重相关的方式显示了三种胃肠肽的分泌曲线。
