Persson K, Boman J
Kliniskt mikrobiologiska laboratoriet, Universitetssjukhuset MAS, Malmö.
Lakartidningen. 1998 May 13;95(20):2334-6, 2339-40.
Infection as a possible underlying cause of atherosclerosis has aroused increasing interest in recent years, Chlamydia pneumoniae being one of the organisms upon which attention has been focused. Newly published results of antibiotic treatment of vascular disease not only appear to provide further support for the infection hypothesis, but also suggest a quite different approach to the treatment of atheromatous cardiovascular disease. However, confirmatory clinical trials will be needed before antibiotic treatment can be considered in such cases.
近年来,感染作为动脉粥样硬化可能的潜在病因已引起越来越多的关注,肺炎衣原体就是其中一个备受关注的病原体。最近发表的血管疾病抗生素治疗结果不仅似乎为感染假说提供了进一步支持,还提示了一种截然不同的动脉粥样硬化性心血管疾病治疗方法。然而,在这类病例中考虑使用抗生素治疗之前,还需要进行验证性临床试验。