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2
Computer simulation of flagellar movement. V. oscillation of cross-bridge models with an ATP-concentration-dependent rate function.鞭毛运动的计算机模拟。V. 具有ATP浓度依赖性速率函数的横桥模型的振荡
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3
Computer simulation of flagellar movement. III. Models incorporating cross-bridge kinetics.鞭毛运动的计算机模拟。III. 包含横桥动力学的模型。
J Mechanochem Cell Motil. 1975;3(2):77-86.
4
A model of flagellar movement based on cooperative dynamics of dynein-tubulin cross-bridges.基于动力蛋白-微管蛋白交叉桥协同动力学的鞭毛运动模型。
J Theor Biol. 1986 Apr 21;119(4):409-33. doi: 10.1016/s0022-5193(86)80192-8.
5
Molecular mechanism for oscillation in flagella and muscle.鞭毛与肌肉中振荡的分子机制。
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10
Computer simulation of flagellar movement IX. Oscillation and symmetry breaking in a model for short flagella and nodal cilia.鞭毛运动的计算机模拟IX. 短鞭毛和节点纤毛模型中的振荡与对称性破缺
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9
Bend propagation in flagella. I. Derivation of equations of motion and their simulation.鞭毛中的弯曲传播。I. 运动方程的推导及其模拟
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Motility of triton-demembranated sea urchin sperm flagella during digestion by trypsin.在胰蛋白酶消化过程中，经曲通（Triton）去膜的海胆精子鞭毛的运动性
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本文引用的文献

1
Effects of increased viscosity on the movements of some invertebrate spermatozoa.粘度增加对某些无脊椎动物精子运动的影响。
J Exp Biol. 1966 Aug;45(1):113-39. doi: 10.1242/jeb.45.1.113.
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Distributed representations for actin-myosin interaction in the oscillatory contraction of muscle.肌肉振荡收缩中肌动蛋白-肌球蛋白相互作用的分布式表征
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Activation in a skeletal muscle contraction model with a modification for insect fibrillar muscle.在骨骼肌收缩模型中的激活，并对昆虫纤维状肌肉进行了修改。
Biophys J. 1969 Apr;9(4):547-70. doi: 10.1016/S0006-3495(69)86403-9.
4
Mechanochemical coupling in flagella. I. Movement-dependent dephosphorylation of ATP by glycerinated spermatozoa.鞭毛中的机械化学偶联。I. 甘油处理的精子中ATP的运动依赖性去磷酸化。
Arch Biochem Biophys. 1968 Jun;125(3):770-8. doi: 10.1016/0003-9861(68)90513-4.
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Bend propagation by a sliding filament model for flagella.鞭毛滑动丝模型中的弯曲传播。
J Exp Biol. 1971 Oct;55(2):289-304. doi: 10.1242/jeb.55.2.289.
6
Computer simulation of flagellar movement. I. Demonstration of stable bend propagation and bend initiation by the sliding filament model.鞭毛运动的计算机模拟。I. 滑动丝模型对稳定弯曲传播和弯曲起始的演示。
Biophys J. 1972 May;12(5):564-86. doi: 10.1016/S0006-3495(72)86104-6.
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Arrangement of subunits in flagellar microtubules.鞭毛微管中各亚基的排列
J Cell Sci. 1974 May;14(3):523-49. doi: 10.1242/jcs.14.3.523.
8
Flagellar movement and adenosine triphosphatase activity in sea urchin sperm extracted with triton X-100.用曲拉通X-100提取的海胆精子中的鞭毛运动和三磷酸腺苷酶活性
J Cell Biol. 1972 Jul;54(1):75-97. doi: 10.1083/jcb.54.1.75.
9
Mechanochemical coupling in flagella. II. Effects of viscosity and thiourea on metabolism and motility of Ciona spermatozoa.鞭毛中的机械化学偶联。II. 粘度和硫脲对玻璃海鞘精子代谢和运动的影响。
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The contractile mechanism of insect fibrillar muscle.昆虫纤维状肌肉的收缩机制。
Prog Biophys Mol Biol. 1967;17:1-60. doi: 10.1016/0079-6107(67)90003-x.

鞭毛运动的计算机模拟。IV. 振荡双态横桥模型的特性。

Computer simulation of flagellar movement. IV. Properties of an oscillatory two-state cross-bridge model.

作者信息

Brokaw C J

出版信息

Biophys J. 1976 Sep;16(9):1029-41. doi: 10.1016/S0006-3495(76)85753-0.

DOI:10.1016/S0006-3495(76)85753-0
PMID:963203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1334943/
Abstract

A stochastic computational method is used to examine the properties of a simple two-state cross-bridge model, of a type which has been shown previously to self-oscillate without requiring any feedback control of the active process. The force transients obtained with this model show the major features observed with oscillatory insect fibrillar flight muscle. The effects of viscosity and cross-bridge detachment rate on the frequency of oscillation of the model resemble the effects of viscosity and ATP concentration on flagellar oscillation, and the relationship between turnover rate and frequency of oscillation is also consistent with observations on flagella. However, the amplitude of oscillation of the model does not show the degree of frequency-independence which is typical of flagella.

摘要

一种随机计算方法被用于研究一个简单的双态横桥模型的特性，该模型此前已被证明能够在不需要对活性过程进行任何反馈控制的情况下自我振荡。用这个模型获得的力瞬变显示出振荡昆虫纤维状飞行肌肉所观察到的主要特征。粘度和横桥解离速率对模型振荡频率的影响类似于粘度和ATP浓度对鞭毛振荡的影响，并且周转率与振荡频率之间的关系也与对鞭毛的观察结果一致。然而，该模型的振荡幅度并未表现出鞭毛典型的频率独立性程度。