Rodríguez Holguín S, Corral M, Cadaveira F
Department of Clinical Psychology and Psychobiology, University of Santiago de Compostela, Galicia, Spain.
Alcohol Alcohol. 1998 May-Jun;33(3):281-90. doi: 10.1093/oxfordjournals.alcalc.a008392.
This article analyses the visual and auditory event-related potentials (ERPs) elicited by infrequent non-target stimuli in young children with alcoholic fathers. The aim was to study the characteristics of the ERP waves specifically evoked by stimuli which capture the attention of the subject in young ones at risk for alcoholism, and to assess the effect of sample factors which can modulate these characteristics, namely family history of alcoholism and gender. There were no differences related to risk for alcoholism on the auditory ERPs. However, males and females with a multigenerational family history of alcoholism showed significant differences on visual ERP latencies, although different waves were affected for each gender. Females showed a larger latency of the visual frontal negative wave, Nc, and males showed a larger latency of the visual parietocentral P300 wave.
本文分析了有酗酒父亲的幼儿对罕见非目标刺激所引发的视觉和听觉事件相关电位（ERP）。目的是研究在有酒精中毒风险的幼儿中，能吸引受试者注意力的刺激所特有的ERP波特征，并评估可调节这些特征的样本因素的影响，即酒精中毒家族史和性别。听觉ERP在与酒精中毒风险相关方面没有差异。然而，有酒精中毒多代家族史的男性和女性在视觉ERP潜伏期上存在显著差异，尽管不同性别受影响的波不同。女性视觉额部负波Nc的潜伏期更长，男性视觉顶中央P300波的潜伏期更长。
