Randell A G, Bhalerao N, Nguyen T V, Sambrook P N, Eisman J A, Silverman S L
Bone and Mineral Research Program, Garvan Institute of Medical Research, St. Vincent's Hospital, Sydney, NSW, Australia.
J Rheumatol. 1998 Jun;25(6):1171-9.
To determine the reliability, consistency, and clinical utility of the Osteoporosis Assessment Questionnaire (OPAQ), an AIMS2 based self-assessment questionnaire.
Reliability of individual questions, scales, and domains were evaluated in 40 subjects by test-retest and intraclass correlation coefficients and internal consistency by Cronbach's alpha. Construct validity was evaluated by disease state. The relationships between domains and scales were modeled by confirmatory factor analysis.
Mean kappa (79 questions) and intraclass correlation (18 health scales) coefficients were 0.58+/-0.16 (mean+/-SD) and 0.82+/-0.07, respectively. Internal consistency was greater than 0.8 in all but 3 scales. Construct validity was confirmed. Patients with hip fracture recorded lower OPAQ scores than patients with vertebral fracture. Correlation and confirmatory factor analyses grouped the 18 health scales into 7 domains.
These findings suggest that OPAQ is a reliable, consistent, and valid instrument capable of distinguishing hierarchy of functional loss in disease states in osteoporosis.
确定基于AIMS2的自我评估问卷——骨质疏松症评估问卷（OPAQ）的可靠性、一致性和临床实用性。
通过重测法和组内相关系数评估40名受试者中各个问题、量表和领域的可靠性，并通过Cronbach's α评估内部一致性。通过疾病状态评估结构效度。通过验证性因子分析对领域和量表之间的关系进行建模。
平均kappa系数（79个问题）和组内相关系数（18个健康量表）分别为0.58±0.16（均值±标准差）和0.82±0.07。除3个量表外，所有量表的内部一致性均大于0.8。结构效度得到证实。髋部骨折患者的OPAQ评分低于椎体骨折患者。相关性分析和验证性因子分析将18个健康量表分为7个领域。
这些发现表明，OPAQ是一种可靠、一致且有效的工具，能够区分骨质疏松症疾病状态下功能丧失的层次结构。
