Suhonen J, Hartiala K, Viljanen M K
Department of Medical Microbiology, Turku University, Turku 20520, Finland.
Infect Immun. 1998 Jul;66(7):3433-5. doi: 10.1128/IAI.66.7.3433-3435.1998.
Interactions between human neutrophils and Borrelia burgdorferi, the Lyme disease spirochete, were studied by dark-field microscopy combined with video technology. A previously unrecognized mechanism for neutrophils to phagocytize the spirochete was discovered. During phagocytosis, the spirochete attaches to the neutrophil head-on, the neutrophil forms a thin tubelike protrusion around the bacterium, and the fully covered spirochete is drawn into the cell.
通过暗视野显微镜结合视频技术研究了人类中性粒细胞与莱姆病螺旋体——伯氏疏螺旋体之间的相互作用。发现了一种中性粒细胞吞噬螺旋体的前所未有的机制。在吞噬过程中,螺旋体正面附着于中性粒细胞,中性粒细胞在细菌周围形成细管状突起,然后将完全被包裹的螺旋体吸入细胞内。