鉴定位于化脓性链球菌毒力因子编码区域的一个插入序列。
Identification of an insertion sequence located in a region encoding virulence factors of Streptococcus pyogenes.
作者信息
Berge A, Rasmussen M, Björck L
机构信息
Section for Molecular Pathogenesis, Department of Cell and Molecular Biology, Lund University, Lund, Sweden.
出版信息
Infect Immun. 1998 Jul;66(7):3449-53. doi: 10.1128/IAI.66.7.3449-3453.1998.
Abstract
An insertion sequence, IS1562, was identified in a Streptococcus pyogenes strain of the clinically important M1 serotype. IS1562 is located in the mga regulon between the genes coding for the M protein and the C5a peptidase, both important virulence factors. The same or similar insertion sequences were found in most S. pyogenes strains, but the chromosomal location differed among isolates.
摘要
在临床上重要的M1血清型化脓性链球菌菌株中鉴定出一种插入序列IS1562。IS1562位于mga调控子中，在编码M蛋白和C5a肽酶的基因之间，这两种都是重要的毒力因子。在大多数化脓性链球菌菌株中发现了相同或相似的插入序列，但不同分离株之间的染色体位置有所不同。
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