Vaughn C E, Leff J P
Br J Psychiatry. 1976 Aug;129:125-37. doi: 10.1192/bjp.129.2.125.
This study is a replication and extension of past work carried out by Brown, Birley and Wing (1972) concerning the influence of family life on the course of schizophrenia. In the original research the index of emotion expressed by a key relative about the patient at the time of key admission proved to be the best single predictor of symptomatic relapse in the nine months after discharge from hospital. In the present study this main finding of Brown et al has been replicated for two clinically different groups of psychiatric patients. The expressed emotion of the relative again seems to be associated with relapse independently of all other social and clinical factors investigated. In addition, important additive effects between various social influences and pharmacological treatments have been revealed which make it possible to predict relapse patterns in schizophrenia with considerable precision. The patterns of these relationships with relapse are different for the two clinical groups studied, patients with schizophrenic psychosis and with depressive neurosis.
本研究是对布朗、伯利和温(1972年)过去所做工作的重复与扩展,该工作涉及家庭生活对精神分裂症病程的影响。在最初的研究中,关键亲属在关键入院时对患者表达的情感指数被证明是出院后九个月内症状复发的最佳单一预测指标。在本研究中,布朗等人的这一主要发现已在两组临床情况不同的精神科患者中得到重复验证。亲属表达的情感似乎再次与复发相关,且独立于所调查的所有其他社会和临床因素。此外,还揭示了各种社会影响与药物治疗之间重要的累加效应,这使得能够相当精确地预测精神分裂症的复发模式。对于所研究的两个临床组,即精神分裂症精神病患者和抑郁性神经症患者,这些与复发的关系模式有所不同。