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[长时间γ射线照射和缺氧对心肌细胞生物电活动的影响]

[Effects of prolonged gamma irradiation and hypoxia on bioelectrical activity of myocardial cells].

作者信息

Lobanok L M, Malykhina A P

机构信息

Institute of Radiobiology, National Academy of Science of Belarus, Minsk.

出版信息

Radiats Biol Radioecol. 1998 Mar-Apr;38(2):201-6.

PMID:9633622
Abstract

It was established that prolonged gamma-irradiation of rats leads to the decrease of amplitude and duration of action potentials of right atrial cells, attenuation of the dependence of these electrophysiological characteristics upon the stimulation frequency, depression of the interval of cardiomyocytes reaction on the hypoxia. The revealed post-radiation changes determine the reduction of function resistance of heart cells bioelectrical activity and promote the initiation of arrhythmias.

摘要

已经确定,对大鼠进行长时间的γ射线照射会导致右心房细胞动作电位的幅度和持续时间降低,这些电生理特性对刺激频率的依赖性减弱,心肌细胞对缺氧反应的间隔时间缩短。所揭示的辐射后变化决定了心脏细胞生物电活动功能抗性的降低,并促进心律失常的发生。

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