Pfau A, Sacks T
Br J Urol. 1976 Aug;48(4):245-53. doi: 10.1111/j.1464-410x.1976.tb03011.x.
6 cases with chronic bacterial prostatitis were reviewed. The effort and patience required to diagnose this condition accurately by means of differential urine and prostatic secretion cultures is extremely worthwhile. Cotrimoxazole, which has been suggested as a most effective antibacterial drug in chronic bacterial prostatitis, cured only 3 out of our 6 patients and then only after continuous treatment for 4 months. 2 of the remaining patients were cured by a 10 to 14 days' course of kanamycin and the third was probably cured by streptomycin. On theoretical grounds neither of these lipid insoluble drugs should be capable of penetrating the prostatic epithelium. The implications of these findings are discussed.
对6例慢性细菌性前列腺炎患者进行了回顾性研究。通过尿液和前列腺分泌物培养进行鉴别诊断这种疾病所需的努力和耐心是非常值得的。在慢性细菌性前列腺炎中，已被认为是最有效的抗菌药物的复方新诺明，在我们的6例患者中仅治愈了3例，且仅在持续治疗4个月后才治愈。其余2例患者通过10至14天的卡那霉素疗程治愈，第3例可能通过链霉素治愈。从理论上讲，这些脂溶性不高的药物都不应能够穿透前列腺上皮。对这些发现的意义进行了讨论。
