Pfau A
Department of Urology, Hadassah Medical Center, Jerusalem, Israel.
Infection. 1991;19 Suppl 3:S160-4. doi: 10.1007/BF01643689.
Chronic bacterial prostatitis, the most common cause of recurrent urinary tract infections in the male patient, is a clinical entity accurately defined by two essential features: (1) recurrent urinary tract infections and (2) persistence of gram-negative bacteria in the prostatic secretion. Chronic bacterial prostatitis is mainly a bacteriologic diagnosis and, therefore, sequential bacteriologic localization cultures are the only way to correct diagnosis. Thirty-five of 39 patients (90%) with chronic bacterial prostatitis were cured of their disease either by a short-term (14-day) intramuscular kanamycin treatment or a long-term (average of five months) oral co-trimoxazole, pure trimethoprim or ciprofloxacin treatment; selected patients suffering from chronic bacterial prostatitis with an associated pathology such as benign enlargement of the prostate, associated occasionally with infected prostatic calculi, who did not respond to medical therapy alone, were cured by a combined adequate antibacterial and surgical (a modified retropubic prostatectomy) treatment. All the patients were followed up for at least one year and most patients several years following treatment.
慢性细菌性前列腺炎是男性患者反复发生尿路感染的最常见原因，它是一种由两个基本特征准确界定的临床实体：（1）反复发生尿路感染；（2）前列腺分泌物中革兰氏阴性菌持续存在。慢性细菌性前列腺炎主要是一种细菌学诊断，因此，连续的细菌学定位培养是正确诊断的唯一方法。39例慢性细菌性前列腺炎患者中有35例（90%）通过短期（14天）肌内注射卡那霉素治疗或长期（平均5个月）口服复方新诺明、单纯甲氧苄啶或环丙沙星治愈；患有慢性细菌性前列腺炎并伴有相关病理情况（如前列腺良性增生，偶尔伴有感染性前列腺结石）且单独药物治疗无效的特定患者，通过联合适当的抗菌和手术治疗（改良耻骨后前列腺切除术）得以治愈。所有患者治疗后至少随访一年，大多数患者随访数年。
