Tzovaras G, Rowlands B J
Department of Surgery, The Queen's University of Belfast, UK.
Br J Surg. 1998 May;85(5):588-95. doi: 10.1046/j.1365-2168.1998.00766.x.
BACKGROUND Sphincter of Oddi dysfunction is a challenge from both the diagnostic and therapeutic point of view. There is much ongoing debate about the accuracy and usefulness of various diagnostic tests, as there is about the effectiveness of proposed therapeutic alternatives.
A comprehensive review of the past 15 years' literature was undertaken, using the Medline database and cross-referencing of major articles on the subject.
Endoscopic and surgical treatments result in similar outcomes, with considerable failure rates. The latter reflect the difficulties in accurate diagnosis and a lack of sound objective criteria for selecting patients for intervention. In addition, in some patients sphincter of Oddi dysfunction may be only part of a generalized motility disorder of the gastrointestinal tract.
背景 从诊断和治疗角度来看,Oddi括约肌功能障碍都是一项挑战。关于各种诊断测试的准确性和实用性存在诸多争论,就像对于所提出的治疗方案的有效性也存在争论一样。
利用Medline数据库对过去15年的文献进行全面回顾,并对该主题的主要文章进行交叉引用。
内镜治疗和手术治疗的结果相似,但失败率相当高。后者反映出准确诊断存在困难,且缺乏为干预选择患者的可靠客观标准。此外,在一些患者中,Oddi括约肌功能障碍可能只是胃肠道普遍运动障碍的一部分。