表达牛瘟病毒核衣壳蛋白的重组痘苗病毒的构建及其在小鼠中的免疫原性。
Construction of recombinant vaccinia virus expressing Rinderpest Virus nucleocapsid protein and its immunogenicity in mice.
作者信息
Ohishi K, Kamata H, Ohkubo S, Yamanouchi K, Kai C
机构信息
Nippon Institute for Biological Science, Tokyo, Japan.
出版信息
J Vet Med Sci. 1998 May;60(5):655-6. doi: 10.1292/jvms.60.655.
PMID:9637306
Abstract
Recombinant vaccinia virus (rVV) was constructed by inserting Rinderpest Virus (RPV) nucleocapsid (N) protein gene. The rVV expressed RPV-N protein in the rVV-infected cells. The rVV was shown to produce RPV-N-specific antibody in mice.
摘要
通过插入牛瘟病毒（RPV）核衣壳（N）蛋白基因构建重组痘苗病毒（rVV）。rVV在感染rVV的细胞中表达RPV-N蛋白。rVV在小鼠体内可产生RPV-N特异性抗体。
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