Saphier C J, Repke J T
Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Semin Perinatol. 1998 Apr;22(2):118-33. doi: 10.1016/s0146-0005(98)80044-x.
Hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome is a form of severe preeclampsia that threatens the gravida and her fetus. In this report, the diagnostic criteria and maternal and fetal risks of HELLP are defined. Prompt recognition and treatment in tertiary centers is emphasized, because the prognosis can be adversely affected by delayed or less than optimal diagnosis and treatment. Management guidelines are offered for treating this disorder. The potential roles of corticosteroids, plasmapheresis, and expectant management are critically evaluated. Subsequent pregnancy outcome, contraception, and preventative strategies are considered.
溶血、肝酶升高和血小板减少（HELLP）综合征是重度子痫前期的一种形式，威胁着孕妇及其胎儿。在本报告中，定义了HELLP的诊断标准以及母婴风险。强调在三级医疗中心进行及时识别和治疗，因为延迟诊断或治疗不充分可能会对预后产生不利影响。提供了治疗该疾病的管理指南。对皮质类固醇、血浆置换和期待治疗的潜在作用进行了严格评估。还考虑了后续妊娠结局、避孕和预防策略。
