Ishikawa M, Masamune O, Yamada H, Takahashi T, Matsuura S
Tohoku J Exp Med. 1976;118 Suppl:89-95. doi: 10.1620/tjem.118.suppl_89.
In order to clarify the abnormal micelle formation in various malabsorption syndromes, the analysis of upper intestinal contents after administering a test meal of Borgström et al. was performed. It was demonstrated that the percentage of micellar fat to total fat and lipase concentrations decreased markedly from the normal controls despite of normal concentrations of bile salts and pH in cases of pancreatitis and pancreatectomy. In contrast, it was shown that the percentage of micellar fat was markedly low and the concentrations of conjugated bile salts were reduced in cases of ileal diseases. Unconjugated bile salts were detected although the concentrations of total bile salts were normal in blind-loop syndrome. The correlation between the percentage of micellar fat and lipase concentrations or bile salts concentrations in normal controls and various malabsorption syndromes was also reported.
为了阐明各种吸收不良综合征中异常微胶粒的形成情况，对博格斯特伦等人的试验餐给药后的上段肠内容物进行了分析。结果表明，在胰腺炎和胰腺切除病例中，尽管胆汁盐浓度和pH值正常，但微胶粒脂肪占总脂肪的百分比和脂肪酶浓度与正常对照组相比显著降低。相比之下，在回肠疾病病例中，微胶粒脂肪的百分比显著降低，结合胆汁盐浓度也降低。在盲袢综合征中，尽管总胆汁盐浓度正常，但仍检测到未结合胆汁盐。还报道了正常对照组以及各种吸收不良综合征中微胶粒脂肪百分比与脂肪酶浓度或胆汁盐浓度之间的相关性。
