Gabre-Selasie S
Department of Medical Microbiology and Parasitology, Jimma Institute of Health Sciences, Ethiopia.
East Afr Med J. 1998 Mar;75(3):175-9.
Moraxella catarrhalis was isolated from 68 of 200 (34%) sputum and 56 (28%) nasopharyngeal swab samples of patients with community-acquired pneumonia. Of the 68 pneumonia patients, 42 (61.8%) were males and 26 (38.2%) females. Fifty one of the 68 patients (75%) had chronic underlying diseases. beta-lactamase was produced by 37 (54.4%) of the 68 sputum samples and 32(57.1%) of the 56 nasopharyngeal isolates. In an ELISA using outer membrane protein antigens of M. catarrhalis against patient sera showed 40 of 68 (58.8%), and 43 of 68 (63.2%) significant increase in convalescent to acute sera when IgA, IgM and IgG3 were used respectively. In control sera only of 30(3.3%) and none showed significant antibody rise when IgA, IgM and IgG3 conjugates were used respectively (P < 0.05).
从200例社区获得性肺炎患者的痰标本中，68例（34%）分离出卡他莫拉菌；从鼻咽拭子标本中，56例（28%）分离出该菌。在这68例肺炎患者中，男性42例（61.8%），女性26例（38.2%）。68例患者中有51例（75%）患有慢性基础疾病。68份痰标本中的37份（54.4%）以及56份鼻咽分离株中的32份（57.1%）产生β-内酰胺酶。在一项使用卡他莫拉菌外膜蛋白抗原针对患者血清的ELISA检测中，当分别使用IgA、IgM和IgG3时，68例患者中有40例（58.8%）、43例（63.2%）恢复期血清相对于急性期血清有显著升高。在对照血清中，当分别使用IgA、IgM和IgG3结合物时，只有30例（3.3%）出现显著抗体升高，且无一例出现显著抗体升高（P<0.05）。
