Allgulander C, Cloninger C R, Przybeck T R, Brandt L
Karolinska Institutet, Huddinge Hospital, Sweden.
Psychopharmacol Bull. 1998;34(2):165-6.
Previously untreated symptomatic volunteers with generalized anxiety disorder (GAD) performed the Temperament and Character Inventory at baseline and after 4 to 6 months of paroxetine treatment. Scores from 29 volunteers were analyzed with paired t-tests. A marked reduction was noted in Harm Avoidance and a marked increase was noted in Self-Directedness. Smaller changes were noted in Cooperativeness and Novelty Seeking. Overall, treatment was associated with a reduction in maladaptive personality traits.
此前未经治疗的有广泛性焦虑症（GAD）症状的志愿者在基线时以及接受帕罗西汀治疗4至6个月后进行了气质与性格问卷测试。对29名志愿者的得分进行配对t检验分析。结果发现，回避伤害得分显著降低，自我导向得分显著升高。合作性和寻求新奇性得分变化较小。总体而言，治疗与适应不良人格特质的减少有关。
