Rosenstock C V, Dahl J B
H:S Rigshospitalet, HovedOrtoCentret, anaestesi- og intensiv afdeling, anaestesiologisk afdeling, Amtssygehuset i Herlev.
Ugeskr Laeger. 1998 Jun 15;160(25):3699-704.
Complications associated with epidural anaesthesia include accidental intravascular or subarachnoid epidural catheter misplacement resulting in systemic toxicity and total spinal block, respectively. Epidural test doses are used routinely to prevent these events. It is not known whether the use of test doses improves the safety of epidural anaesthesia. The reliability of the epinephrine test dose in terms of detecting intravascular injection is impaired in elderly patients, patients receiving beta-blockers, patients undergoing vascular surgery, patients under general anaesthesia, and in women in labour. The ability of the epidural test dose to detect subarachnoid injection remains unknown. Studies are needed to determine 1) the reliability of the epidural test dose among different groups of patients, 2) the safety of the test dose, and 3) the incidence of epidural catheter misplacements.
硬膜外麻醉相关的并发症包括意外血管内或蛛网膜下腔硬膜外导管误置,分别导致全身毒性反应和全脊髓阻滞。硬膜外试验剂量常规用于预防这些情况。目前尚不清楚使用试验剂量是否能提高硬膜外麻醉的安全性。在老年患者、接受β受体阻滞剂治疗的患者、接受血管手术的患者、全身麻醉下的患者以及分娩期妇女中,肾上腺素试验剂量检测血管内注射的可靠性会受到影响。硬膜外试验剂量检测蛛网膜下腔注射的能力尚不清楚。需要开展研究以确定:1)不同患者群体中硬膜外试验剂量的可靠性;2)试验剂量的安全性;3)硬膜外导管误置的发生率。