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[N1 型声门上型喉癌的治疗与结果]

[Treatment and results of N1 supraglottic laryngeal carcinoma].

作者信息

Tong K, Tu G

机构信息

First Hospital of Dalian Medical College.

出版信息

Zhonghua Er Bi Yan Hou Ke Za Zhi. 1996;31(5):307-9.

PMID:9642369
Abstract

One hundred and eleven cases of supraglottic squamous cell cancer (T1-4N1) were retrospectively analysed. The result showed that: 1. the 3 years survival rate was 72% (80/111); 2, the rate of contralateral neck node metastasis after ipsilateral RND was 17.9%, and the cases of T3-4 with positive histologic findings of neck dissection samples had a higher rate contralateral neck node metastasis (38.6%); 3, the contralateral neck node metastasis rate (26.1%) in the group with surgery alone was significantly higher than that (7.1%) in the group with preoperative radiation (P < 0.05). The authors draw the conclusion that contralateral neck node metastasis is a high risk factor for recurrence of N1 supraglottic laryngeal cancer and that preoperative radiation may be be useful in controlling subclinical metastasis.

摘要

对111例声门上型鳞状细胞癌(T1-4N1)患者进行了回顾性分析。结果显示:1. 3年生存率为72%(80/111);2. 同侧根治性颈清扫术后对侧颈部淋巴结转移率为17.9%,颈部清扫标本组织学检查阳性的T3-4病例对侧颈部淋巴结转移率更高(38.6%);3. 单纯手术组的对侧颈部淋巴结转移率(26.1%)显著高于术前放疗组(7.1%)(P<0.05)。作者得出结论,对侧颈部淋巴结转移是N1期声门上型喉癌复发的高危因素,术前放疗可能有助于控制亚临床转移。

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