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塞拉利昂弗里敦小学生中甲型肝炎病毒(HAV)、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和戊型肝炎病毒(HEV)肝炎标志物的血清流行率。

Seroprevalence of hepatitis markers; HAV, HBV, HCV and HEV amongst primary school children in Freetown, Sierra Leone.

作者信息

Hodges M, Sanders E, Aitken C

机构信息

St Andrews Clinics for Children, Freetown, Sierra, Leone.

出版信息

West Afr J Med. 1998 Jan-Mar;17(1):36-7.

PMID:9643158
Abstract

The prevalence of hepatitis markers (Hepatitis A, B, C and E) in primary school children in Freetown, Sierra Leone was investigated in a government school, representative of the urban middle class. The children were aged between 6-12 years old. A sub-sample (n = 120) of the 450 pupils were invited to participate. Of the 66 volunteers (mean 8.32 years) 12 were positive for HBsAg (males 9, females 3) and 11 were confirmed. Six of these were HBeAg positive, anti-HBe negative, (male 5, female 1). Whilst 6 were HBeAg negative, anti-HBe positive (male 4, female 2). HBcAb was present in 47 children (71%). Hepatitis A, C and E antibodies were detected in 64 (97%), 1 (2%) and 5 (8%) of children respectively.

摘要

在塞拉利昂弗里敦一所代表城市中产阶级的政府学校,对小学生中的肝炎标志物(甲型、乙型、丙型和戊型肝炎)流行情况进行了调查。这些儿童年龄在6至12岁之间。从450名学生中抽取了一个子样本(n = 120)邀请其参与。在66名志愿者(平均年龄8.32岁)中,12人HBsAg呈阳性(男性9人,女性3人),其中11人得到确诊。这些人中6人HBeAg阳性、抗-HBe阴性(男性5人,女性1人)。另外6人HBeAg阴性、抗-HBe阳性(男性4人,女性2人)。47名儿童(71%)存在HBcAb。甲型、丙型和戊型肝炎抗体分别在64名(97%)、1名(2%)和5名(8%)儿童中检测到。

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