Sreedevi H, Munshi A K
Department of Pedodontics and Preventive Children Dentistry, A.B. Shetty Memorial Institute of Dental Sciences, Kannada, Karnataka State, India.
J Clin Pediatr Dent. 1998 Winter;22(2):141-6.
During the last decade a lot of attention has been diverted to the study of Actinobacillus actinomycetemcomitans (Aa) as the principal micro-organism in the pathogenesis of periodontal disease. Because of the defective body defenses, there is an increased likelihood of periodontal disease among the Down syndrome patients. An attempt has been made herein to correlate the relationship between the gingival and periodontal health status to the isolation of Aa from the subgingival plaque in Down syndrome cases and to compare it to the neutrophil chemotactic activity to the normal subjects. Strong association between the occurrence of Aa as well as significant differences between the healthy and Down syndrome subjects in neutrophil defense activity were observed.
在过去十年中，人们对伴放线放线杆菌（Aa）作为牙周病发病机制中的主要微生物的研究投入了大量关注。由于身体防御功能缺陷，唐氏综合征患者患牙周病的可能性增加。本文试图将唐氏综合征病例中牙龈和牙周健康状况与龈下菌斑中Aa的分离情况相关联，并将其与正常受试者的中性粒细胞趋化活性进行比较。观察到Aa的出现与中性粒细胞防御活性在健康受试者和唐氏综合征受试者之间存在强关联以及显著差异。
