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英国的乙肝免疫策略——现状如何?

The United Kingdom's hepatitis B immunisation strategy--where now?

作者信息

Goldberg D, McMenamin J

机构信息

Scottish Centre for Infection and Environmental Health, Glasgow.

出版信息

Commun Dis Public Health. 1998 Jun;1(2):79-83.

PMID:9644118
Abstract

The World Health Organization recommended in 1992 that all countries should introduce universal hepatitis B vaccination into their immunisation schedules by December 1997. Over 80 countries, many of them in western Europe, have complied with the recommendation, but, in the United Kingdom (UK), hepatitis B vaccine is offered to selected high risk population groups only. Vaccination uptake in many of these groups is poor and transmission of hepatitis B remains a problem. The current incidence of hepatitis B is lower in the UK than in countries that have adopted a universal approach. It is impossible, however, to predict the number of acute infections that might occur in an unvaccinated teenage population in the year 2015 if the UK's current strategy remains unaltered. Universal immunisation would guarantee that hundreds, if not thousands, of acute illnesses and an appreciable number of severe outcomes would be prevented each year. The authors believe that funding this intervention would be money well spent.

摘要

世界卫生组织于1992年建议,所有国家应在1997年12月前将乙型肝炎普遍疫苗接种纳入其免疫计划。80多个国家,其中许多在西欧,已经遵守了该建议,但在英国,仅向选定的高风险人群提供乙型肝炎疫苗。这些人群中的许多人疫苗接种率很低,乙型肝炎的传播仍然是一个问题。英国目前的乙型肝炎发病率低于采取普遍接种方法的国家。然而,如果英国目前的策略保持不变,就无法预测2015年未接种疫苗的青少年人群中可能发生的急性感染数量。普遍免疫将保证每年预防数百例(如果不是数千例)急性疾病以及相当数量的严重后果。作者认为,为这项干预措施提供资金将是物有所值的。

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