胰腺平滑肌肉瘤。免疫组织化学和流式细胞术研究的病例报告。

Pancreatic leiomyosarcoma. Case report with immunohistochemical and flow cytometric studies.

作者信息

Zalatnai A, Kovács M, Flautner L, Sipos B, Sarkady E, Bocsi J

机构信息

1st Institute of Pathology and Experimental Cancer Research, Semmelweis University of Medicine, Budapest, Hungary.

出版信息

Virchows Arch. 1998 May;432(5):469-72. doi: 10.1007/s004280050193.

DOI:10.1007/s004280050193

PMID:9645448

Abstract

A leiomyosarcoma originating from the pancreas of a 57-year-old man is presented. A 6x5x4 cm tumour was located in the head region, and the patient underwent surgical palliation. Immunohistochemical studies excluded an epithelial origin; a myogenic origin was suggested by strong vimentin and smooth muscle actin positivity. Flow cytometric analysis revealed an aneuploid pattern (DNA index: 1,561). The patient died with widespread metastases 7 month after the operation.

摘要

本文报告一例起源于一名57岁男性胰腺的平滑肌肉瘤。一个6×5×4厘米的肿瘤位于头部区域，该患者接受了姑息性手术。免疫组织化学研究排除了上皮起源；波形蛋白和平滑肌肌动蛋白强阳性提示肌源性起源。流式细胞术分析显示非整倍体模式（DNA指数：1.561）。患者术后7个月死于广泛转移。