Soga J
College of Biomedical Technology, Niigata University, Japan.
J Exp Clin Cancer Res. 1998 Mar;17(1):47-57.
Esophageal endocrinomas are an extremely rare neoplasm. The present study aimed to evaluate multiphasic clinical and pathologic aspects of 100 cases of esophageal endocrinomas, consisting of 28 cases of ordinary type carcinoids and 72 atypical varieties collected from worldwide literature and recorded on computer in the Niigata Registry. The evaluation of esophageal endocrinoma cases was on most occasions carried out in accordance with a comparison between ordinary carcinoids and atypical varieties. Esophageal endocrinomas were generally characterized by a preponderance of male patients and an older age group. They also exhibited a higher metastasis rate, and a lower incidence of carcinoid syndrome than overall endocrinomas of the digestive series. They further indicated a probable unfavorable postoperative outcome as compared to endocrinomas in most other digestive organs. Ordinary carcinoids of the esophagus were characterized by smaller size at detection, lower metastasis rate, and better postoperative outcome than the atypical variety group. Because of the extremely small number of cases of esophageal endocrinomas, additional case reports are in future expected to be satisfactorily documented as a valuable record.
食管内分泌瘤是一种极为罕见的肿瘤。本研究旨在评估100例食管内分泌瘤的多阶段临床和病理特征，其中包括28例普通型类癌和72例非典型类癌，这些病例均收集自全球文献并录入新潟登记处的计算机记录中。对食管内分泌瘤病例的评估大多是通过比较普通类癌和非典型类癌进行的。食管内分泌瘤的一般特征是男性患者居多且年龄较大。与消化系统其他内分泌瘤相比，它们还具有更高的转移率和更低的类癌综合征发病率。与大多数其他消化器官的内分泌瘤相比，它们术后预后可能更差。食管普通类癌的特征是发现时肿瘤较小、转移率较低且术后预后比非典型类癌组更好。由于食管内分泌瘤的病例数量极少，预计未来会有更多病例报告得到令人满意的记录，成为有价值的资料。
