Mills K C, Bean J W
Psychopharmacology (Berl). 1978 Apr 14;57(1):27-31. doi: 10.1007/BF00426953.
Rats housed continuously in a test environment for 25 days were offered water, 5% v/v ethanol, 10% v/v ethanol, and propylene glycol at 7.5% w/v. The propylene glycol concentration represented a caloric midpoint between the 5 and 10% ethanol. After 10 baseline sessions, during which preference for the four solutions was shown to be statistically equal, shock schedules were introduced. The consumption of ethanol at both concentrations showed significant peaks for the interval immediately following 12 min of shock each hour. Intake peaks were not observed for the water or propylene glycol. Baseline blood alcohol levels were negligible, but blood levels under shock averaged 143 mg/dl and ranged from 45.0 mg/dl to 295.0 mg/dl. After the shock sessions were terminated, baseline drinking indicated no significant change in preference relative to pre-shock baselines. but there was an elevation in preference for 5% ethanol relative to the other fluids. The preference for propylene glycol or water did not change.
将持续饲养在测试环境中25天的大鼠提供水、体积分数为5%的乙醇、体积分数为10%的乙醇以及质量体积比为7.5%的丙二醇。丙二醇浓度代表了5%和10%乙醇之间的热量中点。在10次基线实验期间，四种溶液的偏好显示在统计学上是相等的，之后引入了电击程序。两种浓度乙醇的消耗量在每小时电击12分钟后的间隔立即出现显著峰值。水或丙二醇未观察到摄入峰值。基线血醇水平可忽略不计，但电击下的血醇水平平均为143mg/dl，范围为45.0mg/dl至295.0mg/dl。电击实验结束后，基线饮水表明相对于电击前基线，偏好没有显著变化。但相对于其他液体，对5%乙醇的偏好有所升高。对丙二醇或水的偏好没有改变。
