Sarrel P M
Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
Int J Impot Res. 1998 May;10 Suppl 2:S91-3; discussion S98-101.
To describe the use of laser Doppler velocimetry for measurement of vaginal blood flow and report the effects of estrogen compared with estrogen-androgen treatment in post-menopausal women.
Literature review of pelvic blood flow studies and sexual function. Findings from a prospective, randomized, parallel study.
Normal human volunteers in an academic research environment.
Laser Doppler measurements of vaginal blood flow were compared before and after the administration of oral esterified estrogens or esterified estrogens plus methyltestosterone for four and eight weeks of daily drug administration.
Vaginal blood flow velocities.
Laser Doppler velocimetry proved readily adaptable for measurement of vaginal blood flow. Although esterified estrogens plus methyltestosterone showed greater effects on blood flow than esterified estrogens alone, the results were not statistically significant.
Vaginal blood flow is an objective measure of sexual function which can be determined with laser Doppler velocimetry. The vasodilator effects of esterified estrogens and esterified estrogens with methyltestosterone are similar.
描述使用激光多普勒血流仪测量阴道血流量，并报告绝经后女性中雌激素与雌激素 - 雄激素联合治疗的效果比较。
盆腔血流研究和性功能的文献综述。一项前瞻性、随机、平行研究的结果。
学术研究环境中的正常人类志愿者。
在每日口服酯化雌激素或酯化雌激素加甲基睾酮给药四周和八周前后，比较激光多普勒测量的阴道血流量。
阴道血流速度。
激光多普勒血流仪很容易适应测量阴道血流量。虽然酯化雌激素加甲基睾酮对血流的影响比单独使用酯化雌激素更大，但结果无统计学意义。
阴道血流量是性功能的客观指标，可通过激光多普勒血流仪测定。酯化雌激素和酯化雌激素与甲基睾酮的血管舒张作用相似。
