Aleotti A, Cervellati F, Bovolenta M R, Zago S, Orvieto E, Caramori G, Bezzi T
Center of Electron Microscopy, University of Ferrara, Italy.
J Submicrosc Cytol Pathol. 1998 Apr;30(2):295-8.
We investigated the ultrastructure of Birbeck granules which are found in some malignant histiocytoses such as histiocytosis X, Letterer-Siwe disease, Hand-Schüller-Christian disease, eosinophilic granuloma of the bone and self-healing reticulohistiocytosis. The research is based on the systemic study of Birbeck granules, from their formation to intracytoplasmic development, examining with the electron microscope at regular intervals ultrathin sections derived from biopsies of two cases of Langerhans cell histiocytosis.
我们研究了Birbeck颗粒的超微结构，这些颗粒存在于某些恶性组织细胞增多症中，如组织细胞增多症X、勒-雪病、汉-许-克病、骨嗜酸性肉芽肿和自愈性网状组织细胞增多症。该研究基于对Birbeck颗粒的系统研究，从其形成到胞质内发育，定期用电子显微镜检查来自两例朗格汉斯细胞组织细胞增多症活检的超薄切片。
