McKetin R, Mattick R P
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
Drug Alcohol Depend. 1998 Apr 1;50(2):181-4. doi: 10.1016/s0376-8716(98)00022-2.
The purpose of this study was to clarify the extent of neuropsychological impairment previously found among amphetamine users (McKetin and Mattick, 1997) by comparing them with a non-drug-using control group. Amphetamine users who were classified as low dependence (n = 15) or high dependence (n = 11) according to the severity of dependence scale (SDS) were compared to non-drug-using control subjects (n = 9) on indices of the Wechsler Memory Scale-Revised (WMS-R). Dependent amphetamine users (high dependence group) performed approximately one half of a standard deviation worse than controls on the verbal memory, attention/concentration and delayed recall indices of the WMS-R but amphetamine users who were less dependent (low dependence group) showed no impairment.
本研究的目的是通过将苯丙胺使用者与非吸毒对照组进行比较,来阐明先前在苯丙胺使用者中发现的神经心理损害程度(麦凯廷和马蒂克,1997年)。根据依赖严重程度量表(SDS)被分类为低依赖(n = 15)或高依赖(n = 11)的苯丙胺使用者,在韦氏记忆量表修订版(WMS-R)指标上与非吸毒对照受试者(n = 9)进行比较。依赖苯丙胺的使用者(高依赖组)在WMS-R的言语记忆、注意力/集中力和延迟回忆指标上的表现比对照组差约半个标准差,但依赖性较低的苯丙胺使用者(低依赖组)未显示出损害。