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无场梯度的力检测磁共振

Force-detected magnetic resonance without field gradients.

作者信息

Leskowitz G M, Madsen L A, Weitekamp D P

机构信息

A.A. Noyes Laboratory of Chemical Physics, California Institute of Technology, Pasadena 91125, USA.

出版信息

Solid State Nucl Magn Reson. 1998 Mar;11(1-2):73-86. doi: 10.1016/s0926-2040(97)00098-2.

Abstract

A novel method of nuclear magnetic resonance (NMR) is described which promises to be preferable to known general methods at sample length scales below approximately 100 microm. Its advantages stem from the seemingly paradoxical combination of a homogeneous static magnetic field and detection of a mechanical force between a spin-bearing sample and a magnet assembly. In contrast to other methods of force-detected nuclear magnetic resonance (FDNMR), the method is characterized by better observation of magnetization, enhanced resolution, and no gradient (BOOMERANG), and it is generally applicable with respect to sample composition, pulse sequence, and magnetic field strength. Further advantages of portability and low cost stem from the small instrument volume and mass and promise to extend the use of NMR to new applications and environments. A sensitivity analysis, relevant to spectroscopy or imaging, quantifies the advantage of BOOMERANG relative to magnetic induction using microcoils and to FDNMR methods that rely on large gradients of the magnetic field at the sample.

摘要

本文描述了一种新型核磁共振(NMR)方法,在样品长度尺度低于约100微米时,该方法有望优于已知的常规方法。其优势源于均匀静态磁场与检测含自旋样品和磁体组件之间机械力这一看似矛盾的组合。与其他力检测核磁共振(FDNMR)方法相比,该方法具有对磁化的更好观测、更高分辨率且无梯度(BOOMERANG)的特点,并且在样品组成、脉冲序列和磁场强度方面具有普遍适用性。仪器体积小、质量轻带来的便携性和低成本等进一步优势,有望将NMR的应用扩展到新的领域和环境。一项与光谱学或成像相关的灵敏度分析,量化了BOOMERANG相对于使用微线圈的磁感应以及依赖样品处大磁场梯度的FDNMR方法的优势。

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