通过来自北加利福尼亚的自然感染蜱虫（太平洋硬蜱）将马埃里希体实验性传播给马匹。
Experimental transmission of Ehrlichia equi to horses through naturally infected ticks (Ixodes pacificus) from Northern California.
作者信息
Reubel G H, Kimsey R B, Barlough J E, Madigan J E
机构信息
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA.
出版信息
J Clin Microbiol. 1998 Jul;36(7):2131-4. doi: 10.1128/JCM.36.7.2131-2134.1998.
Abstract
We report the experimental transmission of Ehrlichia equi from naturally infected Ixodes pacificus ticks to horses. Three weeks after exposure to ticks, two of three horses developed clinical signs compatible with E. equi infection, while one horse remained asymptomatic. 16S rRNA gene PCR of blood leukocyte lysates was positive for all horses at various time points; two horses seroconverted. The 16S rRNA gene sequences amplified from tick-exposed horses showed more than 99% homology to corresponding fragments of the 16S rRNA genes of E. equi, Ehrlichia phagocytophila, and the human granulocytic ehrlichiosis agent.
摘要
我们报告了马埃里希体（Ehrlichia equi）从自然感染的太平洋硬蜱（Ixodes pacificus）向马的实验性传播情况。在接触蜱虫三周后，三匹马中有两匹出现了与马埃里希体感染相符的临床症状，而一匹马仍无症状。在不同时间点，所有马的血液白细胞裂解物的16S rRNA基因PCR检测均呈阳性；两匹马血清学转换。从接触蜱虫的马中扩增出的16S rRNA基因序列与马埃里希体、嗜吞噬细胞埃里希体及人类粒细胞埃里希体病原体的16S rRNA基因相应片段显示出超过99%的同源性。
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本文引用的文献
1
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J Clin Microbiol. 1998 Jun;36(6):1501-11. doi: 10.1128/JCM.36.6.1501-1511.1998.
2
Guidelines to the demarcation of virus species.病毒种类划分指南。
Arch Virol. 1997;142(7):1505-18.
3
Ehrlichia phagocytophila genogroup rickettsiae in ixodid ticks from California collected in 1995 and 1996.1995年和1996年在加利福尼亚采集的硬蜱中嗜吞噬细胞无形体属立克次体基因组。
J Clin Microbiol. 1997 Aug;35(8):2018-21. doi: 10.1128/jcm.35.8.2018-2021.1997.
4
Transmission of the agent of human granulocytic ehrlichiosis by host-seeking Ixodus scapularis (Acari:Ixodidae) in southern New York state.纽约州南部宿主搜寻性肩突硬蜱（蜱螨亚纲：硬蜱科）传播人粒细胞埃立克体病病原体的研究
J Med Entomol. 1997 Jul;34(4):379-82. doi: 10.1093/jmedent/34.4.379.
5
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