蛋白质折叠：内质网中缺失的氧化还原联系
Protein folding: a missing redox link in the endoplasmic reticulum.
作者信息
Freedman R B, Dunn A D, Ruddock L W
机构信息
Research School of Biosciences, University of Kent, Canterbury.
出版信息
Curr Biol. 1998 Jun 18;8(13):R468-70. doi: 10.1016/s0960-9822(98)70295-7.
PMID:9651676
Abstract
Native disulphide-bond formation during protein folding in the endoplasmic reticulum requires oxidative machinery, the components and mechanism of which are not yet fully understood. Two recent papers have identified a novel protein component that appears to play a key role in this important redox pathway.
摘要
内质网中蛋白质折叠过程中的天然二硫键形成需要氧化机制，其组成成分和机制尚未完全明确。最近的两篇论文鉴定出一种新的蛋白质成分，它似乎在这一重要的氧化还原途径中起关键作用。
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