Dickinson T A, White J, Kauer J S, Walt D R
Department of Chemistry, Tufts University, Medford, MA 02155, USA.
Trends Biotechnol. 1998 Jun;16(6):250-8. doi: 10.1016/s0167-7799(98)01185-8.
Basic principles derived from biological olfaction, such as combining semiselective sensor arrays with pattern recognition, have been used to develop instrumentation capable of broad-band chemical detection and quantification. Commercially available instruments are useful in areas including quality control in the food, beverage and fragrance industries, environmental monitoring, chemical-purity and -mixture analysis, and medical diagnostics. Ongoing research is aimed at the development of more-advanced instruments that are smaller, cheaper, faster and more stable and reliable. These second-generation instruments are likely to find an increasing number of applications, including the on-line monitoring of fermentation and other bioprocesses.
从生物嗅觉中衍生出的基本原理,比如将半选择性传感器阵列与模式识别相结合,已被用于开发能够进行宽带化学检测和定量分析的仪器。市售仪器在食品、饮料和香料行业的质量控制、环境监测、化学纯度和混合物分析以及医学诊断等领域都很有用。正在进行的研究旨在开发更先进的仪器,这些仪器体积更小、成本更低、速度更快、更稳定可靠。这些第二代仪器可能会有越来越多的应用,包括对发酵和其他生物过程的在线监测。