Malatani T S, Batouk A, Teklu B, Irani C, Dewan M, Softah A H, al-Ghamdi B H, Grillo I A
Department of Surgery, College of Medicine King Saud University, Abha, Saudi Arabia.
Indian J Chest Dis Allied Sci. 1997 Oct-Dec;39(4):221-7.
Clinical presentation, pathology, surgical management and follow-up of ten bronchial carcinoid tumour (BCT) patients are described. There were five male and five female patients with age range between 5 to 85 years (mean 39.2 +/- 21.5, SD). Pathology revealed BCT on the right side in seven and on left side in three patients. The tumour was an incidental finding in four while the other six had respiratory symptoms. Cough was present in all of the later group and hemoptysis was present in four patients. Recurrent chest infections were seen in two patients. Symptoms ranged from 1 week to 15 years. Successful surgical resection was done in nine with the longest follow-up of 80 months (mean: 23 months +/- 26.3, SD) without recurrence or metastasis. Histopathological examination of these tumours revealed classical morphological features in all but one case. Grimelius stain positivity for argyrophilia confirmed the diagnosis in all the patients in this study. Electron microscopic examination was done in patient no. 9 which showed atypical morphological features and neurosecretory granules. BCT may present like pneumonias or bronchial asthma. Although BCTs have low-grade malignancy, early diagnosis and surgical resection yield curative results almost in all cases.
本文描述了10例支气管类癌（BCT）患者的临床表现、病理、手术治疗及随访情况。患者共5男5女，年龄范围为5至85岁（平均39.2±21.5，标准差）。病理显示，7例患者肿瘤位于右侧，3例位于左侧。4例患者的肿瘤为偶然发现，其余6例有呼吸道症状。后一组患者均有咳嗽，4例有咯血。2例患者有反复肺部感染。症状持续时间从1周到15年不等。9例患者成功接受了手术切除，最长随访80个月（平均：23个月±26.3，标准差），无复发或转移。除1例外，所有这些肿瘤的组织病理学检查均显示出典型的形态学特征。嗜银性的 Grimelius 染色阳性在本研究所有患者中均证实了诊断。对第9例患者进行了电子显微镜检查，显示出非典型的形态学特征和神经分泌颗粒。BCT可能表现类似肺炎或支气管哮喘。尽管BCT具有低度恶性，但早期诊断和手术切除几乎在所有病例中都能产生治愈效果。
