Conley Y D, Cafoncelli A R, Khan J H, Khan M Z, Aburahma A F, Boland J P
Department of Surgery, Charleston Area Medical Center, West Virginia University.
Am Surg. 1992 Nov;58(11):670-2.
Nineteen cases of bronchial carcinoid tumor seen over 20 years in a 1,000-bed, tertiary medical center were retrospectively reviewed. They consisted of 0.4 per cent of all patients with lung tumors. Initial complaints were hemoptysis, persistent pulmonary infection, chest pain, and diarrhea. Two of the five patients with atypical carcinoid tumors came to the hospital with diarrhea as a result of their chemically active tumors. However, seven patients (36%) were asymptomatic and were diagnosed after an abnormal chest radiograph was noted incidentally. Of 13 patients receiving bronchoscopic examination, 9 (69%) had visible tumors. Bronchial biopsy was performed in 7 patients and led to a diagnosis in all seven. Significant bleeding was noted in 3 patients as a result of biopsy. Lobectomy was the most common surgical procedure in this series. Follow-up of these patients was from 6 months to 15 years. The general outcome for patients with typical carcinoid was good. However, all patients with atypical carcinoid died as a result of dissemination.
对一家拥有1000张床位的三级医疗中心20年间收治的19例支气管类癌肿瘤患者进行了回顾性研究。这些患者占所有肺部肿瘤患者的0.4%。初始症状包括咯血、持续性肺部感染、胸痛和腹泻。五例不典型类癌肿瘤患者中有两例因肿瘤具有化学活性而以腹泻为症状前来就诊。然而,七名患者(36%)无症状,在胸部X光片偶然发现异常后被诊断。13名接受支气管镜检查的患者中,9名(69%)可见肿瘤。7名患者接受了支气管活检,均得以确诊。3名患者活检后出现明显出血。肺叶切除术是该系列中最常见的手术方式。这些患者的随访时间为6个月至15年。典型类癌患者的总体预后良好。然而,所有不典型类癌患者均因肿瘤播散而死亡。