根据糖尿病类型分析口腔扁平苔藓在糖尿病中的患病率。
Prevalence of oral lichen planus in diabetes mellitus according to the type of diabetes.
作者信息
Petrou-Amerikanou C, Markopoulos A K, Belazi M, Karamitsos D, Papanayotou P
机构信息
Department of Oral Pathology and Medicine, Dental School, Aristotle University of Thessaloniki, Greece.
出版信息
Oral Dis. 1998 Mar;4(1):37-40. doi: 10.1111/j.1601-0825.1998.tb00253.x.
OBJECTIVE
The purpose of the present study was to determine the prevalence of oral lichen planus (OLP) in a population of patients with diabetes mellitus (DM) as compared with a control population.
DESIGN
A clinicopathologic study.
SUBJECTS AND METHODS
One hundred and thirty-nine patients with type I DM, 353 patients with type II DM and 274 controls were examined for clinical evidence of OLP. The clinical evidence of OLP in the diabetic and control patients was confirmed by histopathological examination.
RESULTS
The prevalence of OLP in type I diabetic patients was 5.76%, in type II 2.83%, and 1.82% in the controls. The prevalence of OLP was significantly higher in patients with type I DM and slightly higher in patients with type II DM in comparison to the prevalence in the control sample.
CONCLUSIONS
The above findings and the fact that type I diabetes and OLP are characterized by autoimmune phenomena and T cell immune responses respectively, suggest that the immune system may play a critical role in the appearance of OLP in patients with type I DM.
目的
本研究的目的是确定糖尿病（DM）患者群体中口腔扁平苔藓（OLP）的患病率，并与对照人群进行比较。
设计
一项临床病理研究。
对象与方法
对139例I型糖尿病患者、353例II型糖尿病患者和274例对照者进行OLP临床证据检查。糖尿病患者和对照者的OLP临床证据通过组织病理学检查得以证实。
结果
I型糖尿病患者中OLP的患病率为5.76%，II型为2.83%，对照者为1.82%。与对照样本的患病率相比，I型糖尿病患者中OLP的患病率显著更高，II型糖尿病患者中OLP的患病率略高。
结论
上述发现以及I型糖尿病和OLP分别以自身免疫现象和T细胞免疫反应为特征这一事实表明，免疫系统可能在I型糖尿病患者OLP的出现中起关键作用。
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