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女性压力性尿失禁与逼尿肌不稳定之间的可能联系——尿动力学(压力/流量)数据及推测性思考

A possible link between stress urinary incontinence and detrusor instability in the female--urodynamic (pressure/flow) data and speculative considerations.

作者信息

Cucchi A

机构信息

Divisione di Urologia, Policlinico S. Matteo, Pavia, Italy.

出版信息

Int Urogynecol J Pelvic Floor Dysfunct. 1998;9(1):3-8. doi: 10.1007/BF01900532.

DOI:10.1007/BF01900532
PMID:9657171
Abstract

The aim of the present investigation was to check voiding mechanics in women with stress urinary incontinence (SUI) for differences between patients with stable bladders and those with detrusor instability (DI). There were 70 females, 35 with stable and 35 with unstable bladders, who had urodynamically proven SUI. All underwent medium-fill water cystometry and pressure/flow studies. A relatively enhanced detrusor contractility, mirrored by higher values of maximum external voiding power and shortening velocity, could be found in the unstable patients. Of these, 27 were reassessed urodynamically following surgical cure of the SUI. After the operative treatment 17 of the 27 showed stable bladders and a reduced detrusor contractility, but no reduced contractility was found in the other 10, whose bladders remained unstable. The data reported may suggest that the factor responsible for 'idiopathic' DI in SUI patients would also be able to yield enhanced bladder mechanical capability. It was tentatively assumed that this factor involves an increased urethral sensitivity, possibly secondary to incompetence of the urethral closure mechanism, and persisting at times even should SUI be surgically relieved.

摘要

本研究的目的是检查压力性尿失禁(SUI)女性患者的排尿机制,以比较膀胱稳定患者和逼尿肌不稳定(DI)患者之间的差异。共有70名女性,其中35名膀胱稳定,35名膀胱不稳定,她们均经尿动力学证实患有SUI。所有患者均接受了中等容量水囊膀胱测压和压力/流量研究。在不稳定膀胱的患者中,可以发现逼尿肌收缩力相对增强,表现为最大外部排尿功率和缩短速度值较高。其中27名患者在SUI手术治愈后接受了尿动力学复查。手术治疗后,27名患者中有17名膀胱稳定,逼尿肌收缩力降低,但另外10名患者的膀胱仍不稳定,未发现收缩力降低。报告的数据可能表明,导致SUI患者“特发性”DI的因素也可能导致膀胱机械功能增强。初步推测,该因素涉及尿道敏感性增加,可能继发于尿道闭合机制功能不全,甚至在SUI手术缓解后仍有时持续存在。

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