Bartz M, Küpper J, Schultink W, Lukito W, Deurenberg P
Institute for Nutritional Sciences, Rheinische Friedrich-Wilhelms Universität, Bonn, Germany.
Ann Nutr Metab. 1998;42(3):119-26. doi: 10.1159/000012725.
To investigate the validity of the prediction of body water compartments by multi-frequency impedance in Indonesians, 42 adults (19 males and 23 females) were recruited in Jakarta, the capital of Indonesia. Extracellular water (ECW) and total body water (TBW) were measured with dilution techniques and predicted from body impedance at 1 and 100 kHz, respectively, using prediction formulas developed in a Dutch population. Furthermore, body weight, body height and body density were measured and as a measure of body build TBW/height and ECW/height were calculated. Percent ECW of body weight in both males (26 +/- 3%) and females (23 +/- 2%) was higher compared to the Dutch reference population, and also the body water distribution (ECW/TBW) was higher (0.46 +/- 0.04) compared to the reference population. TBW/height and ECW/height appeared to be considerably lower in the Indonesian group compared to the reference group, indicating a more slender body shape. TBW was overestimated by 1.8 +/- 2.4 and 2.5 +/- 1.3 kg in males and females, respectively. ECW was underestimated in males by 0.1 +/- 1.2 kg and slightly overestimated in females (0.1 +/- 1.0 kg). After corrections for differences in body build and body water distribution the bias of the predicted TBW was markedly reduced from 2.2 +/- 1.9 to 1.3 +/- 1.8 kg (males and females combined). For ECW the bias after correction for body water distribution and body build was 0.3 +/- 0.6 kg (males and females combined). It is concluded that multi-frequency impedance is suitable for the prediction of body water compartments at the population level but, due to differences in body build and body water distribution, validation in a larger group of Indonesian subjects is needed to avoid systematic prediction errors.
为研究多频阻抗法预测印度尼西亚人体液分布的有效性，在印度尼西亚首都雅加达招募了42名成年人（19名男性和23名女性）。采用稀释技术测量细胞外液（ECW）和总体液（TBW），并分别使用在荷兰人群中开发的预测公式，根据1 kHz和100 kHz时的身体阻抗进行预测。此外，测量了体重、身高和身体密度，并计算了TBW/身高和ECW/身高作为身体形态的指标。男性（26±3%）和女性（23±2%）的体重细胞外液百分比均高于荷兰参考人群，而且身体水分分布（ECW/TBW）也高于参考人群（0.46±0.04）。与参考组相比，印度尼西亚组的TBW/身高和ECW/身高明显较低，表明身材更为苗条。男性和女性的TBW分别被高估了1.8±2.4 kg和2.5±1.3 kg。男性的ECW被低估了0.1±1.2 kg，女性则被略微高估（0.1±1.0 kg）。在对身体形态和身体水分分布差异进行校正后，预测TBW的偏差从2.2±1.9 kg显著降低至1.3±1.8 kg（男性和女性合并）。对于ECW，在对身体水分分布和身体形态进行校正后的偏差为0.3±0.6 kg（男性和女性合并）。结论是，多频阻抗法适用于在人群水平上预测体液分布，但由于身体形态和身体水分分布的差异，需要在更大规模的印度尼西亚受试者群体中进行验证，以避免系统性预测误差。
