Chen Y, Rennie D C, Lockinger L A, Dosman J A
Dept of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ontario, Canada.
Eur Respir J. 1998 Jun;11(6):1319-23. doi: 10.1183/09031936.98.11061319.
We examined the possible impact of tonsillectomy or adenoidectomy (T/A) on the relationship between environmental tobacco smoke (ETS) exposure and respiratory outcomes. This study was conducted in Humboldt, Saskatchewan, in 1993. The target population included all residents aged 6-17 yrs. Of the 1,019 eligible subjects, 892 participated (88%). Estimates of ETS exposure were based on the reported smoking habits of the children's household members. We defined current cough as a positive response to the question: "Does this child usually have a cough?". Information also included morning cough, night cough and a history of T/A. For children with no history of T/A, the prevalence of current cough was 8.9%, 12.2% and 14.5% for those living in families with 0, 1, and 2+ smokers respectively. The corresponding prevalence was 7.0%, 30.2% and 36.8% for children with history of T/A. Similar effects of ETS exposure were observed on morning cough and night cough. The results did not change significantly when we used various ETS measures and controlled for confounding factors. Compared to children living in nonsmoking families and without history of T/A, the adjusted odds ratio for children with a history of T/A was 7.19 (p<0.001) if they were living in families smoking >20 cigarettes x day(-1) at home. The corresponding odds ratio was only 1.64 (p=0.11) for children without a history of T/A. We concluded that children living in smoking family were more likely to cough than those living in nonsmoking families and tonsillectomy or adenoidectomy increased the apparent influence of environmental tobacco exposure on cough.
我们研究了扁桃体切除术或腺样体切除术（T/A）对环境烟草烟雾（ETS）暴露与呼吸结局之间关系的潜在影响。这项研究于1993年在萨斯喀彻温省的洪堡进行。目标人群包括所有6至17岁的居民。在1019名符合条件的受试者中，892人参与了研究（88%）。ETS暴露的估计基于儿童家庭成员报告的吸烟习惯。我们将当前咳嗽定义为对以下问题的肯定回答：“这个孩子通常咳嗽吗？”。信息还包括晨咳、夜咳以及T/A病史。对于没有T/A病史的儿童，生活在无吸烟者家庭、有1名吸烟者家庭和有2名及以上吸烟者家庭中的儿童当前咳嗽的患病率分别为8.9%、12.2%和14.5%。对于有T/A病史的儿童，相应的患病率分别为7.0%、30.2%和36.8%。在晨咳和夜咳方面也观察到了类似的ETS暴露影响。当我们使用各种ETS测量方法并控制混杂因素时，结果没有显著变化。与生活在无烟家庭且没有T/A病史的儿童相比，如果有T/A病史的儿童生活在在家每天吸烟超过20支的家庭中，其调整后的优势比为7.19（p<0.001）。对于没有T/A病史的儿童，相应的优势比仅为1.64（p=0.11）。我们得出结论，生活在吸烟家庭中的儿童比生活在无烟家庭中的儿童更容易咳嗽，并且扁桃体切除术或腺样体切除术增加了环境烟草暴露对咳嗽的明显影响。
