Kaditis Athanasios G, Finder Jonathan, Alexopoulos Emmanouel I, Starantzis Konstantinos, Tanou Kalliopi, Gampeta Stella, Agorogiannis Eleftherios, Christodoulou Sofia, Pantazidou Anastasia, Gourgoulianis Konstantinos, Molyvdas Paschalis Adam
Pediatric Pulmonology Unit and Sleep Disorders Laboratory, Departments of Pediatrics, Pulmonology, and Physiology, University of Thessaly School of Medicine and Larissa University Hospital, Larissa, Greece.
Pediatr Pulmonol. 2004 Jun;37(6):499-509. doi: 10.1002/ppul.20002.
The goal of the present investigation was to describe the prevalence of and clinical factors associated with sleep-disordered breathing in children and adolescents. Children and adolescents (3,680 in all, 1-18 years old) attending schools in central Greece were surveyed by questionnaires distributed to parents. We found a similar prevalence of habitual snoring (present every night) among three different age groups (5.3%, 4%, and 3.8% in 1-6-, 7-12-, and 13-18-year-old subjects, P = NS). Several children with an adenoidectomy and/or tonsillectomy were snoring every night (6.1%), whereas sleepiness at school was more common in habitual snorers than in nonhabitual snorers (4.6 vs. 2%, P = 0.03). Seventy randomly selected subjects among 307 snorers without adenoidectomy and/or tonsillectomy underwent polysomnography. The estimated frequency of obstructive sleep apnea-hypopnea among children without adenoidectomy and/or tonsillectomy was 4.3%. Factors associated with snoring were: male gender (odds ratio 1.5 (confidence interval, 1.2-1.9)); chronic rhinitis (2.1 (1.6-2.7)); snoring in father (1.5 (1.2-1.9)), mother (1.5 (1.1-2.0)), or siblings (1.7 (1.2-2.4)); adenoidectomy in mother (1.5 (1.0-2.2)); and passive smoking (1.4 (1.1-1.8)). In conclusion, snoring every night was equally prevalent in younger and older ages, more frequent in males, and present even in some children with a history of adenoidectomy and/or tonsillectomy. Chronic rhinitis, family history of snoring, and exposure to cigarette smoke were associated with an increased frequency of habitual snoring.
本研究的目的是描述儿童和青少年睡眠呼吸障碍的患病率及相关临床因素。通过向希腊中部地区学校的家长发放问卷,对3680名1至18岁的儿童和青少年进行了调查。我们发现,在三个不同年龄组中,习惯性打鼾(每晚都有)的患病率相似(1至6岁、7至12岁和13至18岁儿童中分别为5.3%、4%和3.8%,P=无显著性差异)。部分接受过腺样体切除术和/或扁桃体切除术的儿童仍每晚打鼾(6.1%),而习惯性打鼾者在学校出现困倦的情况比非习惯性打鼾者更为常见(4.6%对2%,P=0.03)。在307名未接受腺样体切除术和/或扁桃体切除术的打鼾者中,随机选取70名受试者进行多导睡眠图检查。未接受腺样体切除术和/或扁桃体切除术的儿童中,阻塞性睡眠呼吸暂停低通气的估计发生率为4.3%。与打鼾相关的因素包括:男性(比值比1.5(置信区间1.2至1.9));慢性鼻炎(2.1(1.6至2.7));父亲打鼾(1.5(1.2至1.9))、母亲打鼾(1.5(1.1至2.0))或兄弟姐妹打鼾(1.7(1.2至2.4));母亲接受过腺样体切除术(1.5(1.0至2.2));以及被动吸烟(1.4(1.1至1.8))。总之,每晚打鼾在儿童各年龄段中同样普遍,男性更为常见,甚至在一些有腺样体切除术和/或扁桃体切除术史的儿童中也存在。慢性鼻炎、打鼾家族史以及接触香烟烟雾与习惯性打鼾频率增加有关。